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Host a CF clinical trial in Canada

As a centralized network of paediatric and adult cystic fibrosis trial sites across the country, Cystic Fibrosis Canada Accelerating Clinical Trials Network (CF CanACT), removes barriers and provides the infrastructure and support required for sponsors to conduct trials in Canada.

Two lab technicians working in a Sick Kids laboratory.

Trusted leaders in CF clinical trials

Since inception in 2018, CF CanACT has led CF clinical trials across the country. This nimble network of 10 adult and pediatric clinic-affiliated sites at 13 clinics has direct access to more than half of the people in Canada with cystic fibrosis and is supported by experienced on-site research coordinators for rapid trial start-up, execution and successful trial completion. Through a national referral program, sponsors gain access to 100% of the 4,500+ CF patients in Canada across CF clinics, enabling broad recruitment.

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Cross-Canada Representation

Map of clinical trial locations across Canada

CF CanACT in Review

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Trial Participation

2600+ participants to date

70+ interventional and observational trials

30+ global pharmaceutical organizations

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Recent Milestones

First multi-centre investigator-initiated protocol review conducted by CF CanACT

First NABT trials in the network launched

First pediatric pharmacokinetics study launched by the network

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Built for Every Trial Type

From gene therapy to CFTR modulators to observational studies and more

The process

Our benchmark timelines help to ensure your clinical trial gets moving as quickly as possible:

STEP ONE

Key issues table and critique summary returned to Sponsor within 14 days of submission

STEP TWO

Executive committee (EC) decides on sanctioning and internal strategic fit score within 5 days of Sponsor response to key issues

STEP THREE

Sponsor may choose to accept or appeal the EC’s sanctioning decision

Support referrals

CF CanACT has a well-established referral process to ensure that your trial is well-positioned to meet recruitment targets, no matter where eligible patients are located. CF CanACT also has established relationships with CF clinics that are not affiliated with the research network, which allows patients to be referred into trials happening with CF CanACT from anywhere in Canada.

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